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Pilot study suggests that PrEP for other STIs might work
Gus Cairns, 2015-02-12 08:30:00
A small pilot study using a daily dose of the antibiotic doxycycline as pre-exposure prophylaxis (PrEP) against sexually transmitted infections (STIs) has found that there were 60% fewer STI diagnoses in a group of HIV-positive gay men taking doxycycline compared with men given financial incentives to avoid STIs, a significant difference. There were 71% fewer cases of syphilis, although the small size of the study meant that this difference was nor statistically significant.
The authors suggest that “the use of daily doxycycline against syphilis would.be an appropriate prevention tool…for a relatively small yet epidemiologically important population” of gay men. They add that the 77% overall retention rate in the pilot study “suggests that a clinical trial in a persistently high-risk group” of HIV-positive gay men “is feasible”.
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